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Biblioteca (s) : |
INIA La Estanzuela. |
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Fecha : |
21/02/2014 |
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Actualizado : |
22/02/2014 |
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Autor : |
Dias, M.C. Leme de Lima ; Barros, A.S. do Rego |
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Afiliación : |
Instituto Agronomico do Paraná |
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Título : |
Avaliacao da qualidade de sementes de milho |
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Fecha de publicación : |
1995 |
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Fuente / Imprenta : |
Londrina (Brasil): IAPAR, 1995. |
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Páginas : |
43p. |
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Serie : |
Circular (IAPAR) |
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Idioma : |
Español |
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Thesagro : |
CALIDAD; CONTROL DE CALIDAD; EXPERIMENTACION EN LABORATORIO; MAIZ; SEMILLAS. |
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Asunto categoría : |
-- |
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Marc : |
LEADER 00512nam a2200193 a 4500
001 1036884
005 2014-02-22
008 1995 bl uuuu u00u1 u #d
100 1 $aDIAS, M.C. LEME DE LIMA
245 $aAvaliacao da qualidade de sementes de milho
260 $aLondrina (Brasil): IAPAR$c1995
300 $a43p.
490 $aCircular (IAPAR)
650 $aCALIDAD
650 $aCONTROL DE CALIDAD
650 $aEXPERIMENTACION EN LABORATORIO
650 $aMAIZ
650 $aSEMILLAS
700 1 $aBARROS, A.S. DO REGO
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Registro original : |
INIA La Estanzuela (LE) |
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Biblioteca (s) : |
INIA La Estanzuela. |
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Fecha actual : |
13/09/2017 |
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Actualizado : |
06/12/2018 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
BERTON, MP.; DE OLIVEIRA SILVA, RM.; PERIPOLLI, E.; STAFUZZA ,NB.; MARTIN, JF.; ÁLVAREZ, MS.; GAVINÃ, BV.; TORO, MA.; BANCHERO, G.; OLIVEIRA ,PS.; ELER, JP.; BALDI, F.; FERRAZ, JB. |
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Afiliación : |
Departamento de Zootecnia, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Jaboticabal, Brazil.; Departamento de Zootecnia, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Jaboticabal, Brazil.; Departamento de Zootecnia, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Jaboticabal, Brazil.; Departamento de Zootecnia, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Jaboticabal, Brazil.; Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA, Madrid, España.; Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA, Madrid, España.; Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA, Madrid, España.; Departamento de Producción Agraria, School of Agricultural, Food and Byosystems Engineering, Universisdad Politécnica de Madrid, España.; GEORGGET ELIZABETH BANCHERO HUNZIKER, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; Faculdade de Zootecnia e Engenharia de Alimentos, Nucleo de Apoio à Pesquisa em Melhoramento Animal, Biotecnologia e Transgenia, Universidade de São Paulo, Brasil.; Faculdade de Zootecnia e Engenharia de Alimentos, Nucleo de Apoio à Pesquisa em Melhoramento Animal, Biotecnologia e Transgenia, Universidade de São Paulo, Brasil.; FERNANDO BALDI, Departamento de Zootecnia, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Brazil.; Faculdade de Zootecnia e Engenharia de Alimentos, Nucleo de Apoio à Pesquisa em Melhoramento Animal, Biotecnologia e Transgenia, Universidade de São Paulo,Brasil. |
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Título : |
Genomic regions and pathways associated with gastrointestinal parasites resistance in Santa Inês breed adapted to tropical climate. |
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Fecha de publicación : |
2017 |
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Fuente / Imprenta : |
Journal of Animal Science and Biotechnology , v.8.p. 73.OPEN ACCESS. |
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Descripción física : |
Received: 7 December 2016 Accepted: 12 June 2017 Published: 4 September 2017. |
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DOI : |
10.1186/s40104-017-0190-4 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received: 7 December 2016 //Accepted: 12 June 2017 //Published: 4 September 2017. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
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Contenido : |
Abstract
Background: The aim of this study was to estimate variance components and to identify genomic regions and
pathways associated with resistance to gastrointestinal parasites, particularly Haemonchus contortus, in a breed of
sheep adapted to tropical climate. Phenotypes evaluations were performed to verify resistance to gastrointestinal
parasites, and were divided into two categories: i) farm phenotypes, assessing body condition score (BCS), degree
of anemia assessed by the famacha chart (FAM), fur score (FS) and feces consistency (FC); and ii) lab phenotypes,
comprising blood analyses for hematocrit (HCT), white blood cell count (WBC), red blood cell count (RBC),
hemoglobin (HGB), platelets (PLT) and transformed (log10) egg per gram of feces (EPGlog). A total of 576 animals
were genotyped with the Ovine SNP12k BeadChip (Illumina, Inc.), that contains 12,785 bialleleic SNP markers. The
variance components were estimated using a single trait model by single step genomic BLUP procedure.
Results: The overall linkage disequilibrium (LD) mean between pairs of markers measured by r
2 was 0.23. The overall
LD mean between markers considering windows up to 10 Mb was 0.07. The mean LD between adjacent SNPs across
autosomes ranged from 0.02 to 0.10. Heritability estimates were low for EPGlog (0.11), moderate for RBC (0.18), PLT (0.
17) HCT (0.20), HGB (0.16) and WBC (0.22), and high for FAM (0.35). A total of 22, 21, 23, 20, 26, 25 and 23 windows for
EPGlog for FAM, WBC, RBC, PLT, HCT and HGB traits were identified, respectively. Among the associated windows, 10
were shown to be common to HCT and HGB traits on OAR1, OAR2, OAR3, OAR5, OAR8 and OAR15.
Conclusion: The traits indicating gastrointestinal parasites resistance presented an adequate genetic variability to
respond to selection in Santa Inês breed, and it is expected a higher genetic gain for FAM trait when compared to the
others. The level of LD estimated for markers separated by less than 1 Mb indicated that the Ovine SNP12k BeadChip
might be a suitable tool for identifying genomic regions associated with traits related to gastrointestinal parasite
resistance. Several candidate genes related to immune system development and activation, inflammatory response,
regulation of lymphocytes and leukocytes proliferation were found. These genes may help in the selection of animals
with higher resistance to parasites. MenosAbstract
Background: The aim of this study was to estimate variance components and to identify genomic regions and
pathways associated with resistance to gastrointestinal parasites, particularly Haemonchus contortus, in a breed of
sheep adapted to tropical climate. Phenotypes evaluations were performed to verify resistance to gastrointestinal
parasites, and were divided into two categories: i) farm phenotypes, assessing body condition score (BCS), degree
of anemia assessed by the famacha chart (FAM), fur score (FS) and feces consistency (FC); and ii) lab phenotypes,
comprising blood analyses for hematocrit (HCT), white blood cell count (WBC), red blood cell count (RBC),
hemoglobin (HGB), platelets (PLT) and transformed (log10) egg per gram of feces (EPGlog). A total of 576 animals
were genotyped with the Ovine SNP12k BeadChip (Illumina, Inc.), that contains 12,785 bialleleic SNP markers. The
variance components were estimated using a single trait model by single step genomic BLUP procedure.
Results: The overall linkage disequilibrium (LD) mean between pairs of markers measured by r
2 was 0.23. The overall
LD mean between markers considering windows up to 10 Mb was 0.07. The mean LD between adjacent SNPs across
autosomes ranged from 0.02 to 0.10. Heritability estimates were low for EPGlog (0.11), moderate for RBC (0.18), PLT (0.
17) HCT (0.20), HGB (0.16) and WBC (0.22), and high for FAM (0.35). A total of 22, 21, 23, 20, 26, 25 and 23 windows for
EPGlog for FAM, WBC, RBC, PL... Presentar Todo |
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Palabras claves : |
GWAS; LINKAGE DISEQUILIBRIUM; PARASITES RESISTANCE; RESISTENCIA A PARÁSITOS GASTROINTESTINALES; SANTA INES BREED. |
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Thesagro : |
ENFERMEDADES DE LOS ANIMALES. |
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Asunto categoría : |
L73 Enfermedades de los animales |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/12142/1/Berton-MP.-2017.-Jr.-Animal-Sc.-Biotech..pdf
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Marc : |
LEADER 03896naa a2200373 a 4500
001 1057561
005 2018-12-06
008 2017 bl uuuu u00u1 u #d
024 7 $a10.1186/s40104-017-0190-4$2DOI
100 1 $aBERTON, MP.
245 $aGenomic regions and pathways associated with gastrointestinal parasites resistance in Santa Inês breed adapted to tropical climate.$h[electronic resource]
260 $c2017
300 $cReceived: 7 December 2016 Accepted: 12 June 2017 Published: 4 September 2017.
500 $aArticle history: Received: 7 December 2016 //Accepted: 12 June 2017 //Published: 4 September 2017. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
520 $aAbstract Background: The aim of this study was to estimate variance components and to identify genomic regions and pathways associated with resistance to gastrointestinal parasites, particularly Haemonchus contortus, in a breed of sheep adapted to tropical climate. Phenotypes evaluations were performed to verify resistance to gastrointestinal parasites, and were divided into two categories: i) farm phenotypes, assessing body condition score (BCS), degree of anemia assessed by the famacha chart (FAM), fur score (FS) and feces consistency (FC); and ii) lab phenotypes, comprising blood analyses for hematocrit (HCT), white blood cell count (WBC), red blood cell count (RBC), hemoglobin (HGB), platelets (PLT) and transformed (log10) egg per gram of feces (EPGlog). A total of 576 animals were genotyped with the Ovine SNP12k BeadChip (Illumina, Inc.), that contains 12,785 bialleleic SNP markers. The variance components were estimated using a single trait model by single step genomic BLUP procedure. Results: The overall linkage disequilibrium (LD) mean between pairs of markers measured by r 2 was 0.23. The overall LD mean between markers considering windows up to 10 Mb was 0.07. The mean LD between adjacent SNPs across autosomes ranged from 0.02 to 0.10. Heritability estimates were low for EPGlog (0.11), moderate for RBC (0.18), PLT (0. 17) HCT (0.20), HGB (0.16) and WBC (0.22), and high for FAM (0.35). A total of 22, 21, 23, 20, 26, 25 and 23 windows for EPGlog for FAM, WBC, RBC, PLT, HCT and HGB traits were identified, respectively. Among the associated windows, 10 were shown to be common to HCT and HGB traits on OAR1, OAR2, OAR3, OAR5, OAR8 and OAR15. Conclusion: The traits indicating gastrointestinal parasites resistance presented an adequate genetic variability to respond to selection in Santa Inês breed, and it is expected a higher genetic gain for FAM trait when compared to the others. The level of LD estimated for markers separated by less than 1 Mb indicated that the Ovine SNP12k BeadChip might be a suitable tool for identifying genomic regions associated with traits related to gastrointestinal parasite resistance. Several candidate genes related to immune system development and activation, inflammatory response, regulation of lymphocytes and leukocytes proliferation were found. These genes may help in the selection of animals with higher resistance to parasites.
650 $aENFERMEDADES DE LOS ANIMALES
653 $aGWAS
653 $aLINKAGE DISEQUILIBRIUM
653 $aPARASITES RESISTANCE
653 $aRESISTENCIA A PARÁSITOS GASTROINTESTINALES
653 $aSANTA INES BREED
700 1 $aDE OLIVEIRA SILVA, RM.
700 1 $aPERIPOLLI, E.
700 1 $aSTAFUZZA ,NB.
700 1 $aMARTIN, JF.
700 1 $aÁLVAREZ, MS.
700 1 $aGAVINÃ, BV.
700 1 $aTORO, MA.
700 1 $aBANCHERO, G.
700 1 $aOLIVEIRA ,PS.
700 1 $aELER, JP.
700 1 $aBALDI, F.
700 1 $aFERRAZ, JB.
773 $tJournal of Animal Science and Biotechnology$gv.8.p. 73.OPEN ACCESS.
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